| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 23-08-25 15:30 | Go Ahead Eagles Deventer | Sparta Roterdão | 0:3 |
| 23-08-25 17:45 | PSV Eindhoven | FC Groningen | 4:2 |
| 23-08-25 20:00 | Telstar | FC Volendam | 2:2 |
| 24-08-25 11:15 | SC Heerenveen | FC Twente Enschede | 1:2 |
| 24-08-25 13:30 | NEC Nijmwegen | NAC Breda | 3:0 |
| 24-08-25 13:30 | FC Utrecht | Excelsior Roterdão | 4:1 |
| 24-08-25 15:45 | Ajax Amsterdão | Heracles Almelo | 2:0 |
| 17-09-25 19:00 | Feyenoord Rotterdão | Fortuna Sittard | 2:0 |
| 24-09-25 19:00 | AZ Alkmaar | PEC Zwolle | 2:2 |